Several Cirsium species are known for their uses in traditional medicine and consequently are studied for their phytochemical\ncontent and their biological activities. In the framework of a previous study conducted on eight extremophile plants from Tunisia,\nwe highlighted that the crude methanolic extract of C. scabrum, a not investigated thistle, showed moderate but quite selective\ncytotoxic activity against the cancerous cell line J774 compared to the noncancerous cell line WI38 (IC50 = 11.53
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